Biodiagnostics: Particle Sorting
The miniaturisation of fluidic systems for chemical and biological analysis has become an important research field. The goal is to produce hand-held biodiagnostic laboratories which can be taken to the patient, this has particular advantages in the developing world. The area is collectively termed micro total analysis systems (μTAS) or “lab on a chip.” The first stage of analysing a sample is to sort the particulate matter (eg cells or pathogens), the separate components can then be quantified.
Biochemistry: Sample Handling
The miniaturisation of fluidic systems for chemical and biological analysis has an important research field. The goal is to produce systems capable of multiple different reagents with a sample to interrogate biological response for development of microbiological research into cell and pathogen behaviour. A chip will be developed to dispense tiny volumes of sample; technologies then be investigated to merge these droplets with multiple reagents so that assays can be formed.
Biodiagnostics: Sample Concentration
Microfluidic systems offer the possibility of reducing laboratory scale experimental processes a device the size of a chip. A key motivation for this is the possibilities it offers in testing, both in terms of improved accuracy and in performing response analysis which is not possible at large scales. In many biomedical tests the chemical solution in which are suspended is changed to examine response, the challenge is to do this at the with the advantage that small length scales mean very fast changes and hence time related data.